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Gheisari,Yousof; Soleimani,Masoud; Zeinali,Sirous; Arefian,Ehsan; Atashi,Amir; Nikougoftar Zarif,Mahin. |
The kidney has an inherent ability for recovery and regeneration following acute damage. However, there has been much contention as to the source of regenerating renal cells. The aim of this study was to isolate and characterize these cells. Normal rat kidneys were minced and cells were isolated with collagenase I and were cultured in an expansion medium. Adherent cells were isolated and expanded for more than 120 days in vitro. These cells had the potential of translineage differentiation into neural cells, adipocytes and osteocytes. These cells also expressed Nucleostemin, Cyclin D1, Notch1 and Survivin which are commonly expressed in stem cells. The results of the current work show that the adult kidney contains a population of multipotent stem cells. |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Kidney failure; Regeneration; Cell differentiation; Renal replacement therapy. |
Ano: 2009 |
URL: http://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0327-95452009000100004 |
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Lugon,J.R.; Pereira,G.R.M.; Strogoff-de-Matos,J.P.; Peixoto,A.J.. |
Details about the acid-base changes in hemodialysis are scarce in the literature but are potentially relevant to adequate management of patients. We addressed the acid-base kinetics during hemodialysis and throughout the interdialytic period in a cross-sectional study of adults undergoing conventional hemodialysis. Samples for blood gas analysis were obtained from the arterial limb of the arteriovenous fistula before the first session of the week (HD1), immediately at the end of HD1, and on sequential collections at 15, 30, 45, 60, and 120 min post-HD1. Additional blood samples were collected after ∼20 h following the end of the first dialysis and immediately prior to the initiation of the second dialysis of the week. Thirty adult patients were analyzed... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Hemodialysis; Renal replacement therapy; Kinetics; Adequacy of dialysis; Acid-base. |
Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2019000100611 |
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